000 02930cam a22003374a 4500
001 vtls000306586
003 UG-KaMUL
005 20250613003330.0
016 _a015985877
_2 Uk
020 _a9780195387889 (hardback)
020 _a0195387880 (hardback)
039 _a201805041246
_b 952
_c 201802271234
_d 638
_c 201211300801
_d 901
_c 201209191112
_d 916
_y 201205161522
_z958
040 _aDLC
_b eng
_d YDX
_d UKMGB
_d BDX
_d TPH
_d CUX
_d CHS
_d YDXCP
_d C OO
_d CDX
_d UG-KaMUL
060 _aQV 771
_b M514c 2012
082 _a616.0750724
_2 23
084 _aMED106000
_a MED028000
_2 bisacsh
100 _aMeinert, Curtis L.
245 _a Clinical trials :
_bdesign, conduct, and analysis /
_cCurtis L. Me inert.
250 _a2nd ed.
260 _aNew York :
_bOxford University Press,
_c c2012.
300 _axxxv, 665 p. :
_bill. ;
_c 26 cm.
490 _aMonographs in epidemiology and biostatistics ;
_v 39
504 _aIncludes bibliographical references and index.
520 _a"First published in 1986, this landmark text is the definitive guide to clinical trials, written by one of the leading experts in the field . This fully-updated second edition continues to be the most authoritat ive reference text on randomized clinical trials. It contains a wealth of practical information on the design, conduct, and analysis of both s ingle center and multicenter trials. No other book on clinical trials o ffers as much detail on such issues as sample size calculation, stratif ication and randomization, data systems design, development of consent forms, publication policies, preparation of funding requests, and repor ting procedures. While the basics of design, conduct, and analysis of c linical trials remain the same, there have been significant changes sin ce the first edition of Clinical Trials was published two decades ago. In this new edition, the author discusses the refinements and improveme nts made to methods and procedures, changes in the policies and guideli nes underlying trials, as well as requirements for registration of tria ls. He also discusses current practices for data sharing, for gender re presentation, for treatment effects monitoring, and for ethical standar ds of clinical trials. The importance of the randomized controlled tria l has grown significantly over time and they are now the cornerstone of all evidence-based medicine. Still rich in tables, checklists, charts, and other resources for the trialist, the second edition of Clinical T rials is an indispensable reference for clinicians, biostaticians, epid emiologists, and anyone involved in the design and implementation of a clinical trial"--Provided by publisher.
650 _aClinical trials.
650 _a Clinical Trials as Topic
830 _aMonographs in epidemiology and biostatistics ;
_v v. 39.
942 _2ddc
_cBK
999 _c549903
_d549903