Immunobiology : the immune system in health and disease /
Char les A. Janeway, Jr. .. [et al.].
- 6th ed.
- New York : Garland Science, c2005.
- xxiii, 823 p. : ill. (col.) ; 28 cm. +1 CD-ROM (4 3/4 in.)
Includes bibliographical references and index.
Pt. 1. An introduction to immunobiology and innate immunity. Basic c oncepts in immunology -- Innate immunity. -- Pt. 2. The recognition of antigen. Antigen recognition by B-cell and T-cell receptors. -- The gen eration of lymphocyte antigen receptors. -- Antigen presentation to T l ymphocytes. -- Pt. 3. The development of mature lymphocyte receptor rep ertoires. Signaling through immune system receptors. -- The development and survival of lymphocytes. -- Pt. 4. The adaptive immune response. T cell-mediated immunity. -- The humoral immune response. -- Adaptive im munity to infection. -- Pt. 5. The immune system in health and disease. Failures of host defense mechanisms. -- Allergy and hypersensitivity. -- Autoimmunity and transplantation. -- Manipulation of the immune resp onse. -- Pt. 6. The origins of immune responses. Evolution of the innat e immune system.