Fundamentals of forensic DNA typing / John M. Butler.
Material type:
TextPublication details: Amsterdam ; Boston : Academic Press/Elsevier, c2010.Description: xviii, 500 p. : ill. ; 24 cmISBN: - 9780123749994 (pbk. : alk. paper)
- 0123749999 (pbk. : alk. paper)
- 614/.1 22
- W 786
Based on author's Forensic DNA typing : biology & technology behind STR markers. c2001.
Includes bibliographical references and index.
Overview and history of DNA typing -- Basics of DNA biology and gene tics -- Historical methods -- Sample collection, storage, and character ization -- DNA extraction -- DNA quantitation -- DNA amplification (the polymerase chain reaction) -- Short tandem repeat markers -- Fundament als of DNA separation and detection -- STR genotyping and data interpre tation -- Statistical interpretation : evaluating the strength of foren sic DNA evidence -- DNA databases -- Quality assurance -- Forensic chal lenges : degraded DNA, mixtures, and LCN -- Additional loci and nonhuma n DNA testing -- Lineage markers : Y chromosome and mtDNA testing -- Ap plications of DNA typing -- Future trends.
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