Medical biochemistry at a glance / Jack G. Salway.
Material type:
TextSeries: At a glancePublication details: Malden, Mass. : Blackwell Pub., 2006.Edition: 2nd edDescription: 144 p. : ill. ; 28 cmISBN: - 9781405113229 (alk. paper)
- 1405113227 (alk. paper)
- 612.015 22
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Rev. ed. of : Medical biochemistry at a glance / Ben Greenstein, Ada m Greenstein. 1996.
Includes bibliographical references and index.
Acids, bases and hydrogen ions (protons) -- Understanding pH -- Prod uction and removal of protons into and from the blood -- Metabolic acid osis and metabolic alkalosis -- Respiratory acidosis and respiratory al kalosis -- Amino acids and the primary structure of proteins -- Seconda ry structure of proteins -- Tertiary and quaternary structures: collage n -- Enzymes: nomenclature, kinetics and inhibitors -- Regulation of en zyme activity -- Carbohydrates -- Absorption of carbohydrates and metab olism of galactose -- Oxidation/reduction reactions, coenzyme and prost hetic groups -- Anaerobic production of atp by substrate-level phosphor ylation, phosphocreatine, adenylate kinase -- Aerobic production of ATP -- Biosynthesis of ATP by oxidative phosphorylation I -- The biosynthe sis of ATP by oxidative phosphorylation II -- What happens when protons or electrons leak from the respiratory chain? --
Free radicals, reactive oxygen species and oxidative damage -- Aerob ic oxidation of glucose to provide energy as ATP -- Anaerobic oxidation of glucose by glycolysis to form ATP and lactate -- Anaerobic glycolys is in red blood cell, 2,3 BPG and the Bohr effect -- The fate of glucos e in liver: glycogenesis and lipogenesis -- Fructose metabolism -- Gluc ose homeostasis -- Glucose-stimulated secretion of insulin from the bet a-cell -- Regulation of glycogen metabolism -- Glycogen breakdown (glyc ogenolysis and glycogen storage diseases) -- Insulin signal transductio n and diabetes mellitus -- Regulation of glycolysis and Krebs cycle -- Oxidation of fatty acids to produce ATP in muscle and ketone bodies in liver -- Regulation of lipolysis, beta-oxidation, ketogenesis and gluco neogenesis -- Diabetes mellitus -- Alcohol metabolism: hypoglycemia, hy perlactataemia and steatosis -- Structure of lipids -- Phospholipids I --
Phospholipids II: micelles, liposomes, lipoproteins and membranes -- Metabolism of carbohydrate and fat to cholesterol -- VLDL and LDL meta bolism ("forward" cholesterol transport) -- VLDL and LDL metabolism (en dogenous triacylglycerol transport) -- HDL metabolism ("reverse" choles terol transport) -- Digestion and disposal of dietary triacylglycerol a nd cholesterol by chylomicrons -- Steroid hormones: aldosterone, cortis ol, androgens and oestrogens -- Urea cycle and overview of amino acid c atabolism -- Nonessential and essential amino acids -- Amino acid metab olism: to energy as ATP; to glucose and ketone bodies -- Amino acid dis orders: maple syrup urine disease, homocystinuria, alkaptonuria and alb inism -- Phenylalanine and tyrosine metabolism in health and disease -- The products of tryptophan and histidine metabolism -- Pyrimidine meta bolism -- Purine metabolism -- Haem, bilirubin and porphyries -- Fat-so luble vitamins I --
Fat-soluble vitamins II -- Water-soluble vitamins 1 thiamin. ribofla vin, niacin and pantothenate -- Water-soluble vitamins 2 pyridoxal phos phate -- Water-soluble vitamins 3 folate and vitamin B12 -- Water-solub le vitamins 4 biotin and vitamin C.
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