Basic immunology : functions and disorders of the immune system / Abul K. Abbas, Andrew H. Lichtman ; illustrated by David L. Baker a nd Alexandra Baker.
Material type:
TextPublication details: Philadelphia, PA : Saunders/Elsevier, c2009.Edition: 3rd edDescription: viii, 312 p. : ill. ; 24 cmISBN: - 9781416046882
- 1416046887
- QW 504
Includes bibliographical references (p. 239-243) and index.
Introduction to the immune system: the nomenclature, general propert ies, and components of the immune system -- Innate immunity: the early defense against infections -- Antigen capture and presentation to lymph octyes: what lymphocytes see -- Antigen recognition in the adaptive imm une system: structure of lymphocyte antigen receptors and the developme nt of immune repertoires --
Cell-mediated immune responses: activation of T lymphocytes by cell- associated microbes -- Effector mechanisms of cell-mediated immunity : eradication of intracellular microbes -- Humoral immune responses: acti vation of B lymphocytes and production of antibodies -- Effector mechan isms of humoral immunity: the elimination of extracellular microbes and toxins --
Immunological tolerance and autoimmunity: self-nonself discriminatio n in the immune system and its failure -- Immune responses against tumo rs and transplants: immunity to noninfectious transformed and foreign c ells -- Hypersensitivity: disorders caused by immune responses -- Conge nital and acquired immunodeficiencies: diseases caused by defective imm une responses.
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